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A CASE WITH HYPOCRETIN(OREXIN) DEFICIENT NARCOLEPSY, PARKINSON’S DISEASE AND SEVERE PSYCHOSIS WAS SUCCESSFULLY TREATED BY MODIFIED ELECTRO-CONVULSIVE THERAPY

Abstract

We report the case of a 60-year-old male who exhibited severe psychosis two years after beginningtreatment with methylphenidate for hypocretin deficient narcolepsy. He also suffered fromParkinson’s disease (PD) and was treated by several medications. The psychotic episode persistedseveral weeks after medication cessation and required management with modified electroconvulsiontherapy. Physicians should be aware that psycho-stimulants and anti-PD medicationscommonly prescribed for treatment of narcolepsy and PD may precipitate psychosis in thosepatients

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