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Complications Encountered with a Transfemorally Placed Port-Catheter system for Regional Chemotherapy of Hepatobiliary-Pancreatic Tumors

Abstract

Purpose: To determine the rate of complications associated with a port-cathetersystem implanted via the femoral arterial access for hepatic arterial chemotherapeuticinfusion.Materials and Methods: One-hundred thirteen patients with liver metastases andprimary hepato-biliarypancreatic tumors underwent the procedure. The infusion catheterwas connected to a port implanted subcutaneously below the level of the inguinalligament.Results: Implantation of the system was successful in 107 of 113 patients (94.7%). Wedid not treat with infusion chemotherapy on 5 of 107 patients because of poor generalcondition. The observation period after placement ranged from 4 to 787 days (mean 233days). Complications after system placement were observed in 18 of 102 patients (17.6%),These included hepatic arterial injury (7.8%) with a mean system use of 361 days (range24-671 days), pocket trouble (4.9%) with a mean ,system use of 253 days (range 21-624days), port-catheter system obstruction (3.9%) with a mean system use of 100 days(range 62-263 days) and significant catheter dislodgement from the target artery (2.9%)with a mean system use of 384 days (range 358-436 days).Conclusion: Our data suggested that it was feasible and safe to place the port-cathetersystem percutaneously via the femoral artery

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