Abstract: Background and aim: Cancer is the third leading cause of mortality in Iran. By use of Geographic
Information System, location-based and accurate analytical and descriptive date can be given to health policy
makers. The aim of this study is to identify the incidental patterns of cancers (random, scattered, cluster) and
analyze them spatially. Method(s): This is a periodical descriptive and analytical study which has investigated
all new recorded incidents of cancers in Chaharmahal and Bakhtiari Province in southwestern Iran from 2008
to 2011. The data were analyzed using ArcGIS9.3 and Stata12. Spatial Auto correlation coefficient and Moran
I and Getis-Ord, t test, ANOVA and Chi-square were used for data analysis. Results revealed that in the age
Mean and Standard deviation of the patients was 5/81 ±9/59. The mean age of the patients was meaningful
according to gender and different towns (P=0.037). Standardized Incidences of Cancer in Shahrekord, Farsan,
Ardal, Kiar, Koohrang, Lordegan and Borougen towns were 220/9, 154/3, 143/8, 80/9, 64/2, 61/1 and 57/2 per one
hundred thousand of population, respectively. The most frequency of cancers was related to cancers of the
digestive system ((2/25%, skin(2/81%)and urinary system (9/85%) and the least of them was related to
cartilage(3/0%). Patterns of cancer incidence in southwestern Iran was random (P=0.13519). In Conclusions:
Reports of differences in cancer incidence based on age, sex, city of residence and non-cluster cancers in the
area studied can support the cancer prevention and screening programs focusing hypothesis and pave the road
for decision makers and planners in the health system
