ANTI-FUNGAL EFFECT OF HYDROALCOHOLIC EXTRACT OF ECHINOPHORA PLAYLOBA ON CANDIDA ALBICANS

Abstract

The endemic Plants have different applications among people. Echinophora Platyloba is used in folk medicine, as a food seasoning. This study conducted to evaluate the effect of hydroalcoholic extract of Echinophora platyloba on Candida albicans. Materials and Methods: By perculation method, hydroalcoholic extract was obtained. There 5 tubes of different diluted solution of extract were made as: 0, 35, 50, 150, 250 mg/ml for test. The yeast was purchased from faculty of medicine of Isfahan Unuiversity of Medical Sciences. By using agar dilution method, the yeast inoculated into all media for after 21 days of incubation period, when, the results were recorded. The yeast was grown in control tube but no growth was observed in media containing difference diluitions of extract. The results showed that 35, 50 and 150 mg/ml may have clinical application. This preliminary study showed that ethanolic extract of Echinophora platyloba has anti Candida albicans effect and may be in used in production of drug and clinical assay