Pain is a distressing feeling caused by damage to different tissues. Consequently
the person reacts, and tries to remove the painful stimulus.
On the other hand, prostaglandins contribute to the emergence of pain.
These compounds are formed and secreted by cyclogenase 2 or COX-2
enzymes. It is through inhibiting these enzymes that most of the analgesic
medications act. Thus, this study aims to investigate and review
some of the scientific findings on analgesic effects and possible active
ingredients and analgesic mechanisms of these herbs. Result: Nowadays
one of the methods to control pain is using non-steroid anti-inflammatory
medications. Although the analgesic effects of these medications emerge
relatively fast, but their side effects are considered to be a limiting factor
in their usage. Therefore researchers are constantly in the search of new
medications with less side effects. In recent years the tendency to use
herbal medications has significantly increased in the treatment and prediction
of these diseases. Since analgesic medications show a wide range
of complications therefore using secondary herbal compounds may be an
appropriate alternative for chemical medications. In this respect, many
analgesic effects of herbal medications have been brought into attention
and it is believed that many natural compounds may serve as new medical
compounds.Conclusion: Regarding the importance of research about pain
and the effort in increasing awareness in this respect and also regarding
the problems caused by using opioid medications, it is necessary to find
herbal medications