Background and aims: Primary varicella infection which is rarely seen among infants appears as chicken pox in children and zona in adults due to its reactivation. Considering its rarity in infants, an 8-month case infected with varicella due to reactivation of intrauterine primary infection is reported. Case report: An 8-month infant with 3200gr weight at a vaginal delivery was hospitalized for erythematous lesion around the left eye, diagnosed as orbital cellulitis initially. The lesion spread rapidly to 8×14cm and several fluid -filled vesicules (which then turned into yellow) developed. Referring to case history, the mother was infected to varicella with generalized macrovesicular lesions involving stomach, face, and limbs. Infant tests of varicella zoster virus about the existence of immunoglobulin M were positive. Treatment was done by cephalotine, acyclovir, and sulfacetamide eye drop. The lesions disappeared within one week. Conclusion: In this patient, because of exposure to varicella infection in utero period, reactivation of primary infection after birth in 8-month appeared herpes zoster symptoms. After diagnosis, the treatment was successful
