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The effect of Fig on antioxidant and oxidative parameter of normal young men in a clinical trial study

Abstract

Background and aim: Today, due to the increased production of free radicals such as pollution, there is a need to a good antioxidant resource. Fig which is one of the fruit mentioned in the Qur'an, may prevent increased production of free radicals because of its rich content of antioxidants. This study was aimed to study the effect of using figs on oxidant and antioxidant parameters on healthy young men. Materials and methods: In this clinical trial, 74 healthy male students were chosen randomly and divided into two groups of test and control. Age range was 18- 40, and residency in university’s dormitories were entry criteria and disease, smoking and taking other complements were exclude criteria. The test group receive daily 120 g dried fig for four weeks. Blood samples were obtained from two groups at beginning of study and after 4 weeks. Total Antioxidant Capacity (TAC) was measured by FRAP method, activity of GGT and the rate of Fe were matured by auto analyzer system BT 3000. Results: results indicate that Fe level has a significant decrease as an oxidative parameter in the test group (N= 37) after four weeks of interference (p=005/0). GGT and TAC levels showed a significant increase as antioxidant parameters in the test group after four weeks of interference (p= 0/001). Conclusion: Considering the significant decrease in Fe level as the oxidative parameter and substantial increase in GGT and TAC level as the antioxidant parameters, Figs can play an effective and useful role in increasing the antioxidant defend of the body against free radicals and so decrease damages caused by oxidative stress

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