Abstract Introduction: Bladder cancer is the most common tumor of the urinary tract and the ninth cancer in terms of incidence in both sexes in the world. Bladder cancer is the second most common cancer in men in Iran. This study aimed to investigate the trend of death from bladder cancer in Iran. Materials and Methods: This study was conducted by the use of data on mortality in Iran during 2006-10. Data on mortality from cancer within the study period were collected and entered on a pre-designed form. Mortality rates per 105 persons were calculated by age group and sex, and the trend of mortality from this cancer was determined. Results: The results from the calculation of mortality rates per 105 persons indicated that the death rate from bladder cancer is reduced from 1.12 to 1.09. The mortality rates during all the years under study showed that increasing age increases bladder cancer in men. Discussion: No particular change was observed in the analysis of the trend of tobacco use in Iran in the last two decades, which can be considered as one of the causes of constancy of mortality trend from bladder cancer. However, given the increase in the number of people over 65 and the observed growing trend in bladder cancer incidence in various regions of the country, it is recommended that health policies are adopted in order to prevent risk factors behind this type of cancer such as tobacco and harmful industrial materials
