Pain is an unpleasant sensory experience which is developed by acute or potential tissue damage. Currently, some
drugs such as nonsteroidal anti-inflammatory drugs such as aspirin and ibuprofen, opioids such as morphine,
meperidine, methadone, tramadol, buprenorphine, butorphanol, and nalbuphine as well as other drugs including
tricyclic antidepressants and corticosteroids are being used to control pain. These drugs could cause side effects.
Given the high prevalence of toothache and that a variety of plants are used to relieve toothache in Iranian
traditional medicine, this study was conducted to document the data of medicinal plants effective on relief of
toothache in Shiraz. In this study, the data on traditional treatments were gathered from the groceries across Shiraz
between 23 July, 2015 and 23 October, 2015 by pre-developed questionnaires administered to the grocers by
researcher. The data obtained from the questionnaires were meticulously tabulated and recorded and analyzed by
Excel. Finally 20 plants from 14 families were identified as being used for toothache in Shiraz. Most plants effective
on toothache were from Composite family. Aerial parts were (38%) were the most frequently used organs and
concentrated extract (70%) was the most frequent traditional method of use in the studied region. Papaver
tennifolium (37.03%) obtained the highest percentage of frequency of citation of the toothache-relieving plants in
Shiraz. It is necessary to identify the effective substances in the medicinal plants native to Shiraz used to relieve
toothache and to study these substances' therapeutic effects
