Between 1889 and 1916, the U. S. Fish Commission steamer Albatross made numerous trips to waters off southern California, particularly in and near San Diego Bay. The typical pattern for many years was to conduct cruises in waters off the Pacific Northwest or Alaska in summer months and waters off southern California in winter months. The Albatross conducted the first depth soundings and benthic profiles for southern California waters and secured the first samples of many endemic marine animals of this region. Albatross collections formed the basis for numerous definitive monographs of invertebrates and vertebrates that were published in subsequent years. The Albatross anchored in San Diego Bay in 1894, conducting the first biological investigations of the bay, and returned to sample again in many subsequent years. The ship and its crew also examined Cortez and Tanner banks for exploitation potential and conducted the first biological investigations of southern California’s tuna stocks in 1915 and 1916