Metoclopramide is a drug that has been used in the dose of 10 mg iv for postoperative
nausea and vomiting (PONV) prophylaxis for many years and has been reported to be ineffective
at this dose. That a higher dose of this drug, when used in combination with 8 mg
dexamethasone, is more effective when compared with 8 mg dexamethasone only is worth
validating and this study was designed to do. The aim is to compare the effectiveness of adding
50 mg metoclopramide (in two divided doses) to 8 mg intravenous dose of dexamethasone
versus 8 mg dexamethasone only as a prophylactic anti-emetic in gynaecological surgery under
spinal anaesthesia at University of Ilorin Teaching Hospital, Ilorin
