The genetic engineering resistance movement in New Zealand constructed strategic and meaningful interpretations of why the genetic engineering technique is problematic and what can be done about it. There are four central interpretations – explored here as collective action frames – that were used by key movement activists in their mobilisation activities. These four frames describe genetic engineering as ‘involving a wide range of issues’, ‘risky’, ‘unnatural’ and as ‘all about the ownership of life’. The characteristics of these frames are explained in this paper, along with an analysis of why it is that activists were able to achieve widespread resonance through their deployment of them. The successful framing and articulation of movement grievances is a critical movement activity for engagement of civil society in issues of great importance