Detection of foreign nucleic acids is a crucial component
of innate immunity against viruses. For that purpose, cells are
equipped with a repertoire of cytoplasmic and membrane-bound
DNA/RNA sensors. Recognition of non-self nucleic acids leads to
the activation of downstream pathways dedicated to elimination or
containment of infection. One of the strategies to counteract viral
infections is the production of interferons, the cytokines which alert
neighboring cells about potential threats.(...)Fundação Calouste Gulbenkia
