This thesis proposes a reference model to describe the components of an Un-manned Air, Ground, Surface, or Underwater System (UxS), and the use of a single Interoperability Building Block to command, control, and get feedback from such vehicles. The importance and advantages of such a reference model, with a standard nomenclature and taxonomy, is shown. We overview the concepts of interoperability and some efforts to achieve common refer-ence models in other areas. We then present an overview of existing un-manned systems, their history, characteristics, classification, and missions. The concept of Interoperability Building Blocks (IBB) is introduced to describe standards, protocols, data models, and frameworks, and a large set of these are analyzed. A new and powerful reference model for UxS, named RAMP, is proposed, that describes the various components that a UxS may have. It is a hierarchical model with four levels, that describes the vehicle components, the datalink, and the ground segment. The reference model is validated by showing how it can be applied in various projects the author worked on. An example is given on how a single standard was capable of controlling a set of heterogeneous UAVs, USVs, and UGVs
