In 2005, the first codling moth (CM) populations with a reduced susceptibility to Cydia pomonella granulovirus
(CpGV) products have been observed. This phenomenon might be an indicator of an emerging resistance of
CM to CpGV. This paper summarizes some aspects of CM CpGV interaction and discusses potential
mechanisms in the host virus interaction, which could contribute to the observed low susceptibility. In order to
develop and implement successful resistance management strategies, much more knowledge about the
plasticity of CM CpGV interaction and the diversity of CM populations is essential