Research into fetal development and medicin

A Faisal-Cury

A Tabor

AC Huizink

ACMG

AK Bij van der

AT Wittman

Audrey B. C. Coumans

Brigitte H. W. Faas

C Lewis

Caterina M. Bilardo

D Oepkes

Dick Oepkes

EJH Mulder

Eva Pajkrt

G. C. M. Lieve Page-Christiaens

HL Bekker

Irene M. van Langen

J Gitsels-van der Wal

J Taylor

Klaske D. Lichtenbelt

L Chew

Lean Beulen

Lidewij Henneman

M Allyse

M Vanstone

Marjon A. de Boer

Merel C. van Maarle

Merryn V. E. Macville

MM Gil

N Nakata

P Brady

P Sarkar

RA Mancuso

Rachèl V. van Schendel

RV Schendel van

S Chetty

S Lou

S Michie

S Mikamo

S Nakic Rados

S Tamminga

TM Marteau

W Dondorp

Increasingly, high-risk pregnant women opt for non-invasive prenatal testing (NIPT) instead of invasive diagnostic testing. Since NIPT is less accurate than invasive testing, a normal NIPT result might leave women less reassured. A questionnaire study was performed among pregnant women with elevated risk for fetal aneuploidy based on first-trimester combined test (risk >/=1:200) or medical history, who were offered NIPT in the nationwide Dutch TRIDENT study. Pre- and post-test questionnaires (n = 682) included measures on: experiences with NIPT procedure, feelings of reassurance, anxiety (State-Trait Anxiety Inventory, STAI), child-related anxiety (PRAQ-R), and satisfaction. The majority (96.1%) were glad to have been offered NIPT. Most (68.5%) perceived the waiting time for NIPT results (mean: 15 days, range 5-32) as (much) too long. Most women with a normal NIPT result felt reassured (80.9%) or somewhat reassured (15.7%). Levels of anxiety and child-related anxiety were significantly lower after receiving a normal NIPT result as compared to the moment of intake (p < 0.001). Women with inadequate health literacy or a medical history (e.g. previous child with trisomy) experienced significantly higher post-test-result anxiety (Mean (M) STAI = 31.6 and 30.0, respectively) compared to those with adequate health literacy (M = 28.6) and no medical history (M = 28.6), indicating these women might benefit from extra information and/or guidance when communicating NIPT test-results. Introducing NIPT as an alternative to invasive testing, led to an offer that satisfied and largely reassured high-risk pregnant women

Schendel, R.V. van

Page-Christiaens, G.

Beulen, L.

Bilardo, C.M.

Boer, M.A. de

Coumans, A.B.C.

Faas, B.H.W.

Langen, I.M. van

Lichtenbelt, K.D.

Maarle, M.C. van

Macville, M.V.E.

Oepkes, D.

Pajkrt, E.

Henneman, L.

NARCIS 

Women's Experience with Non-Invasive Prenatal Testing and Emotional Well-being and Satisfaction after Test-Results

Increasingly, high-risk pregnant women opt for non-invasive prenatal testing (NIPT) instead of invasive diagnostic testing. Since NIPT is less accurate than invasive testing, a normal NIPT result might leave women less reassured. A questionnaire study was performed among pregnant women with elevated risk for fetal aneuploidy based on first-trimester combined test (risk >= 1:200) or medical history, who were offered NIPT in the nationwide Dutch TRIDENT study. Pre- and post-test questionnaires (n = 682) included measures on: experiences with NIPT procedure, feelings of reassurance, anxiety (State-Trait Anxiety Inventory, STAI), child-related anxiety (PRAQ-R), and satisfaction. The majority (96.1%) were glad to have been offered NIPT. Most (68.5%) perceived the waiting time for NIPT results (mean: 15 days, range 5-32) as (much) too long. Most women with a normal NIPT result felt reassured (80.9%) or somewhat reassured (15.7%). Levels of anxiety and child-related anxiety were significantly lower after receiving a normal NIPT result as compared to the moment of intake (p <0.001). Women with inadequate health literacy or a medical history (e.g. previous child with trisomy) experienced significantly higher post-test-result anxiety (Mean (M) STAI = 31.6 and 30.0, respectively) compared to those with adequate health literacy (M = 28.6) and no medical history (M = 28.6), indicating these women might benefit from extra information and/or guidance when communicating NIPT test-results. Introducing NIPT as an alternative to invasive testing, led to an offer that satisfied and largely reassured high-risk pregnant women

van Schendel, Rachèl V

Page-Christiaens, G C M Lieve

Beulen, Lean

Bilardo, Caterina M

de Boer, Marjon A

Coumans, Audrey B C

Faas, Brigitte H W

van Langen, Irene M

Lichtenbelt, Klaske D

van Maarle, Merel C

Macville, Merryn V E

Oepkes, Dick

Pajkrt, Eva

Henneman, Lidewij

Golberg, Michael A

Elsevier - Publisher Connector 

A generalized invariant imbedding equation II 

University of Groningen Research Database

Increasingly, high-risk pregnant women opt for non-invasive prenatal testing (NIPT) instead of invasive diagnostic testing. Since NIPT is less accurate than invasive testing, a normal NIPT result might leave women less reassured. A questionnaire study was performed among pregnant women with elevated risk for fetal aneuploidy based on first-trimester combined test (risk ≥1:200) or medical history, who were offered NIPT in the nationwide Dutch TRIDENT study. Pre- and post-test questionnaires (n = 682) included measures on: experiences with NIPT procedure, feelings of reassurance, anxiety (State-Trait Anxiety Inventory, STAI), child-related anxiety (PRAQ-R), and satisfaction. The majority (96.1%) were glad to have been offered NIPT. Most (68.5%) perceived the waiting time for NIPT results (mean: 15 days, range 5–32) as (much) too long. Most women with a normal NIPT result felt reassured (80.9%) or somewhat reassured (15.7%). Levels of anxiety and child-related anxiety were significantly lower after receiving a normal NIPT result as compared to the moment of intake (p < 0.001). Women with inadequate health literacy or a medical history (e.g. previous child with trisomy) experienced significantly higher post-test-result anxiety (Mean (M) STAI = 31.6 and 30.0, respectively) compared to those with adequate health literacy (M = 28.6) and no medical history (M = 28.6), indicating these women might benefit from extra information and/or guidance when communicating NIPT test-results. Introducing NIPT as an alternative to invasive testing, led to an offer that satisfied and largely reassured high-risk pregnant women

van Schendel, Rachèl V.

Page-Christiaens, G. C.M.Lieve

Bilardo, Caterina M.

de Boer, Marjon A.

Coumans, Audrey B. C.

Faas, Brigitte H.W.

van Langen, Irene M.

Lichtenbelt, Klaske D.

van Maarle, Merel C.

Macville, Merryn V. E.

Women’s Experience with Non-Invasive Prenatal Testing and Emotional Well-being and Satisfaction after Test-Results

for the Dutch NIPT Consortium

Utrecht University Repository

Michael A Golberg

MUCC (Crossref)

A generalized invariant imbedding equation II

van Schendel, Rachel V.

Page-Christiaens, G. C. M. Lieve

Faas, Brigitte H. W.

University of Groningen

Contains fulltext :
                  182689.pdf (publisher's version ) (Open Access)Increasingly, high-risk pregnant women opt for non-invasive prenatal testing (NIPT) instead of invasive diagnostic testing. Since NIPT is less accurate than invasive testing, a normal NIPT result might leave women less reassured. A questionnaire study was performed among pregnant women with elevated risk for fetal aneuploidy based on first-trimester combined test (risk >/=1:200) or medical history, who were offered NIPT in the nationwide Dutch TRIDENT study. Pre- and post-test questionnaires (n = 682) included measures on: experiences with NIPT procedure, feelings of reassurance, anxiety (State-Trait Anxiety Inventory, STAI), child-related anxiety (PRAQ-R), and satisfaction. The majority (96.1%) were glad to have been offered NIPT. Most (68.5%) perceived the waiting time for NIPT results (mean: 15 days, range 5-32) as (much) too long. Most women with a normal NIPT result felt reassured (80.9%) or somewhat reassured (15.7%). Levels of anxiety and child-related anxiety were significantly lower after receiving a normal NIPT result as compared to the moment of intake (p < 0.001). Women with inadequate health literacy or a medical history (e.g. previous child with trisomy) experienced significantly higher post-test-result anxiety (Mean (M) STAI = 31.6 and 30.0, respectively) compared to those with adequate health literacy (M = 28.6) and no medical history (M = 28.6), indicating these women might benefit from extra information and/or guidance when communicating NIPT test-results. Introducing NIPT as an alternative to invasive testing, led to an offer that satisfied and largely reassured high-risk pregnant women

Radboud Repository

file:///data/remote/core/dit/data/elsevier/pdf/1a2/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS8wMDIyMjQ3eDcxOTAwOTkw.pdf

A generalized invariant imbedding equation II

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NARCIS

NARCIS

Elsevier - Publisher Connector

University of Groningen Research Database

NARCIS

Utrecht University Repository

MUCC (Crossref)

NARCIS

University of Groningen

Radboud Repository