Bronsvoort, B.M. de C.

Cook, Elizabeth A.J.

Fèvre, Eric M.

Glanville, William A. de

Kariuki, S.

Thomas, Lian F.

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Table 1 Prevalence of leptospirosis   Slaughterhouse Zoonoses Leptospirosis and Q fever in Kenya  E.A.J. Cook1,2, W.A. de Glanville1,2, L.F. Thomas1,2, B.M.D. Bronsvoort3, S. Kariuki4 and E.M. Fèvre2,5   Globally slaughterhouse workers are high risk due to contact with animals  No previous studies in Kenya investigating zoonoses in slaughterhouse workers  Poor hygiene practices contribute to transmission of zoonotic diseases  Background Materials and methods 1 Centre for Infectious Diseases and Centre for Immunity,  Infection and Evolution, University of Edinburgh, Ashworth Laboratories, West Mains Rd, Edinburgh, EH9 3JT UK 2 International Livestock Research Institute (ILRI), Old Naivasha Road, PO Box, 30709-00100,  3 Epidemiology, Economics and Risk Assessment Group, The Roslin Institute,  University of Edinburgh, Easter Bush, EH25 9RG, UK 4 Centre for Microbiology Research,  Kenya Medical Research Institute PO Box 54840 , 00100, Nairobi, Kenya Objective Identify risk factors associated with zoonotic disease exposure in slaughterhouse workers  Outcomes  Prevalence of leptospirosis and Q fever   Risk factors associated  with exposure Study site 45km radius from Busia, Kenya  Study population 142 slaughterhouses 738 slaughterhouse workers Sampling procedure Questionnaire  Risk factors  Knowledge of zoonoses  Biological samples Blood Sample analysis  Panbio Leptospira IgM ELISA (Alere, Australia)   Classic Coxiella bur-netii Phase 2 IgG ELISA (Serion, Ger-many) Data analysis  Mixed effects multi-variable logistic re-gression    Risk maps created using Kernel smoothing Results Fig 1 Map of slaughterhouses in study area in western Kenya Zoonoses Prevalence n=738 95% CI Leptospirosis 13.4%  11.1-16.1 Thanks to the MRC, Wellcome Trust and the University of Edinburgh for supporting this work  Conclusions   Slaughterhouse workers in western Kenya exposed to leptospirosis and Q fever   Poor hygiene practices associated with exposure   Identified risk factors will be used to develop targeted interventions  Targeted interventions discussed with local veterinary and public health officials  5 Institute of Infection and Global Health, University of Liverpool, Leahurst Campus, Neston, CH64 7TE, UK Risk factor OR 95 % CI Having wounds 2.7 1.4-5.3  Smoking at work 1.8 1.1-3.0  Eating at work 2.1 1.2-3.6  Cleaning intestines 3.8 1.8-8.2 Antemortem exam 0.6 0.4-0.9 Slaughterhouse >5 workers 2.4 1.2-4.7 Workers wear protective clothing (PPE) 0.3 0.2-0.5 Table 4 Significant risk factors for  Q fever  Table 2 Significant risk factors for  leptospirosis Zoonoses Prevalence n=738 95% CI Q fever 4.5%  3.2-6.2 Table 3 Prevalence of Q fever  Risk factor OR 95 % CI Intoxicated at work  3.2 1.1-9.4 Workers wear protective clothing 0.3 0.1-0.9 Fig 2 Risk maps of lepto (left) and Q fever in workers Risk  

Slaughterhouse zoonoses: Leptospirosis and Q fever in Kenya

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Slaughterhouse zoonoses: Leptospirosis and Q fever in Kenya

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