. Multiple-Intelligences-Based (MIB) instruction is an instruction applied to encourage students\u27 growth and development of multiple intelligence. This study aims to investigate the effect of MIB instruction theory on metacognition awareness and learning outcome in Biology instruction of students. A quasi experimental design was used. Non random sampling was applied based on the research population that covered the student of SMPN 11 Mataram, which resulted VIIIA as the experimental class and VIIIF as the controlled class. In order to determine the effect of MI-based instruction compared with traditional instruction, observation sheets were utilized to assess lesson plan accomplishment. In order to assess the metacognition awareness of the learners in Biology subject, the Metacognitive Awareness Inventory (MAI) was employed and to assess the Biology learning outcome that consisted of multiple-choice test. A t-test for independent sample was used to compare experimental and control groups post-test results. The results of the study indicated that MIB instruction had a significant effect on metacognition awareness and Biology learning outcome of VIII grade students of SMPN 11 Mataram compared with conventional instruction
