Nilai Trombosit Pada Pasien Penyakit Ginjal Kronik Yang Menjalani Hemodialisis Di Unit Hemodialisis Bagian/smf Ilmu Penyakit Dalam Fk Unsrat Blu Rsup Prof. Dr. R. D. Kandou Manado

Abstract

: Bacground: Stadium V Chronic Kidney Disease is less than 15 ml/mnt GFR, there is an accumulation of toxin uremia in blood that could harm the survival of patient, it is required a substitute therapy for the kidney,which is called hemodialysis. Hemodialisis needs anticoagulation, so blood clotting in circuit extracorporeal does not occur. In its development, have been tried several kinds of anticoagulation technique and anticoagulant which is made based on the state of the patient such as heparin, but in its using it can cause side effects. The work of heparin as anticoagulant dependents on anti thrombin (AT-III) that is an inhibitor of various factor of clotting. Heparin can cause changing of homeostasis because of its effect to the function of thrombosis ( thrombosis aggregation ) even to reduce the number of thrombosis ( Heparin Induced Thrombocytopenia ) . Purpose: To know and to study about the value of thrombosis in CKD patient who endure hemodialysis in unit hemodialisis Department of Internal Medicine BLU RSUP Prof. Dr.R.D. Kandou Manado.Method : Descriptive retrospective, using secondary data medic record in unit hemodyalisis Department of Internal Medicine BLU RSUP Prof. DR .R. D. Kandou Manado. Result: The thrombocytopenia patient increased on HD > 96 X, most of them are men in range 51 – 60 years old. Conclusion: CKD patient who endure hemodyalisis generally have normal thrombosis value, number of thrombocytopenia case is 25,45 % and number of most occurrence is commonly to me