Infection, especially extra pulmonary tuberculosis, remain the leading cause of fever of unknown origin (FUO). FUO is defined as temperature higher than 38.3 ºC with duration of fever of more than 3 weeks. We reported a case of liver tuberculosis, whose had fever more than 38.3 ºC in 2 months. A liver biopsy and histology evaluation have performed revealing liver tuberculosis. The patient received oral anti-tuberculosis agents. But after three days of anti-tuberculosis treatment, the patient experience jaundice. The patient was diagnosed as a drug induced hepatitis. After adjusted regimen of oral anti- tuberculosis, the patient's condition improved. The patient was back home with good conditions
