Requerey Jiménez, Verónica

Universitat Autònoma de Barcelona. Facultat de Veterinària

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Verónica Requerey JiménezMain hormone secreting adrenal tumors in dogs and cats- Facultat de Veterinària de la UAB – June 30th 2016 -Bibliographic study of the three most common adrenal tumors in dogs and cats (hyperadrenocorticism, pheochromocytoma, hyperaldosteronism), approaching the subject from thepathophysiology to recent studies about diagnosis and treatment.Adrenal primary tumors represent 1-2% ofall canine tumors, being less common incats, representing only 0.2%. Thanks tothe greater availability of imagingtechniques like ultrasounds, computedtomography (CT) and magnetic resonanceHyperadrenocorticism•PU/PD,polyphagia, Pheochromocytoma•Asymptomatic or Hyperaldosteronism•Weakness, neckimaging (MRI), the diagnosis of adrenaldiseases has improved. Despite this,adrenal diseases remain emergingillnesses often diagnosed as incidentalfindings or in necropsy room .panting,abdominalenlargement,endocrinealopecia.•Increased AP , ALT, cholesterol  and hypertensionlethargy, weight loss,  anorexia, panting, PU/PD, tachypnea,tachycardia.• Hypertension. ventroflexion , PU/PD.•Hypertension, hypokalemia.Abdominal UltrasoundAdrenal mass Radiography MetastaseslymphomaLow-Dose dexamethasone suppression testor  ACTH stimulation testPlasma-free metanephrineand free normetanephrine measurementAldosterone: Renin RatioThese three diseases sometimesshow non-specific clinical signsmaking it confusing and complicatedto reach an adrenal disease diagnose.Positive NegativeAdrenal HACNegative PositivePheochromocytomaNegative PositiveSecondary PrimaryBecause of that, it could be includedin the diagnostic protocol of thesecases, an ultrasound examination ofadrenal glands. This way, adrenaldamage could be discarded andmisdiagnosis or empirical treatmentscould be avoided.RemovabletumorUnresectabletumorSex hormonesNonfunctionaltumorRemovabletumorUnresectabletumorHyperaldosteronismNonfunctionaltumorHyperaldosteronismRemovable tumorUnresectabletumorThe implementation of blood pressuremesure in physical examinationscould be useful in the suspicion of acortical or medular tumor that risessystholic pressure.Publication of veterinary clinicalAdrenalectomy TrilostaneGranuloma,abscess,myelolipomas, hematomasAdrenalectomy Phenoxybenzaminegranuloma,abscess,myelolipomas, hematomas AdrenalectomyPotassium gluconate,SpironolactoneAmplodipine,cases and the advances in humanmedicine can be also useful andguide to new lines of investigation andimprove our diagnosis andtreatments.

Main hormone secreting adrenal tumors in dogs and cats

https://ddd.uab.cat/pub/tfg/2016/174912/TFG_vrequereyjimenez_poster.pdf

Main hormone secreting adrenal tumors in dogs and cats

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