Dengue hemorrhagic fever (DHF) which is transmitted through the bite of mosquito Aedes aegypti and Aedes albopictus females still becomes a health problem, especially in Indonesia. Repellant is used to avoid interference or bite of the Aedes aegypti mosquito. The purposes of this research are to determine the repellency of the ethanolic extract of betel leaf lotion with lanolin variation as a basis toward Aedes aegypti, to determine whether the ethanolic extract of piper betel leaves lotion with lanolin variation as a basis irritate the test animals or not, and to compare the influence of lanolin concentration toward physical characteristic of lotion. Piper betel leaves extracted with 96% ethanol, using reflux. The ethanolic extract of piper betel leaves used in the formula lotion is 5%. This lotion was made into 3 formula with lanolin concentration difference 3%, 4% and 5%. Lotion ethanolic extract of piper betel leaves had been made then evaluated physically, repellency and irritation. Dispersive and viscosity of the lotion will determine the convenience of the use by human. Differences of lanolin concentration in each formula lotion, greatly affect the viscosity, dispersive, adhesion and repellency each formula. Repellency lotion ethanolic extract of piper betel leaves is 88% in 11 minutes. The primary irritation index lotion ethanolic extract of piper betel leaves is 0,33. Concentration of lanolin is proportional to the lotion repellant the ethanolic extract of piper betel leaves. The primary irritation index lotion ethanolic extract of piper betel leaves is 0,33 or few stimulating. Concentration of lanolin inversely to the value of dispersive, but it is directly proportional to the value of adhesion and viscosity lotion.
Keywords : repellency, irritation, lotion, ethanolic extract of piper betel leaves (Piper betle Linn
