Islami, Atefeh

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dl".r!,,o.lilrd ob*i 9 Ob.f ,o.sif n* ol$iilog, olnsl urui€. .r$i;, c.tSiJlo&li irg-Q,dJ^t =Sliy,.gl;fs gls c,il11s cqr: gfgie1l1ol **1lil A.rt*il t d Clhro 11 sJy{ jl cJui di €h.")q Jljjgf l.rQ .tr} / .+rllfttJl,{:o sb-f c&{ tI*15 q o*;f c+lr olSj Js: ln;ll1$l*lo9i.f;ls loT fs prti rlSrol! s*1G lrrJ.t5o .SGT rlUt: d.rl$ g r,iagt!sn)t f 4iblelf12 ota;o:6.us.2ceiJ ui.atS !*>9. af c*l ,-llyl+ t" o?-t * g-LJ, o!-5.-i jl (5s{ lllcl ,r-;-l (51$;l ,r' : aoJ'ia.gta ;Lrc c9.L-* ooti:ul ,trcl ,r-,:-l .5,t.i;l ., ..rL.lr sn o);-fl d .f-b Gy )l.r5'- '':':rf- .rls;,c ,:J a5 c*l F?t{c pS 9 ts-" Gss.i- (pure platelet rich plasma) Pm Ol.. ,rrl -,,1 af r-l Jy'-4 ,c PRP Jl;rgllrt &,i -rib G-D l-JlL^;,-l ;l -i.ro. c^l a:sf )li c.JtL' 9 t?;-t cr9"" a'r-; ;'l. u;l* .+ ,lr,:l ,r-;-l dll.:.>l .d ,:L,Jcst) ..,frb ,lc uoLii .*J! ,gt ;1 ,S Gy + u5 .!iqr" pilot a,Jtt .51 *ltL 6,l : to .;il)g ct9.\. 9 PRP Jl;r9l-,t,.irr coa , 69.i1 os-F P tt+r t' ala.;9 u"i pQ-l SUI a, >t-"',*'U rl-* V'6,5.,,9 .r.::e.S rlr-i (mid urethral sling a*; .Slf) SUI .:rlsL-l 6Lr': ;:'; J;;S o9f t'> 'Q. (ICIQ) ,lrcl .grt*:il d 6r-.r a-.rc ,rllJl O+ a-oL,r -r, J*^SJ 41.-9 { .-.rLtr 1l ,-y-- oL t 9 \ gl-lL'rt,sr)il (QUDI) .grlrsl .5rt :-l o, ;.ru.i a-L-i;,'.,, I (IQOL) ,lrcl .5r[il ,.J .J$i c+J a-L::-;..r; pta.:l (cough stress test) +ir-Y 9 a;iil.: r# .-sr9*d ,y-ti;lgr-, (/.Y'l;';Y PRP l*;Lr': c''; os.F t4 \' ;1 ;l : 61liip A mid urethral sling ,r>lr- l* ,-:L-rr co6 o9f .,lqt t' Cr..t -tl , 'r'': r'1.$ .Ft" t {Jd 0'f ')F.r;t|f rl, PRP .5r+ 6b 19c ! 6Lrs c.=; a.f c5;lq: Y ;l .-r*l.u 6r4.t.e Y r a:"i'|": "['tf 6r9'.{rtr9>9 _rl.:1,- o ogli; o9f 9J _r$ .rJ ;Lr.: 1l r+ 9 Ji Lo a.L. * ,,; 61LJ ;r..1jlf l.+" .-f"5 .5.:94; p Ymid ! ;Lrc c.-* og-5 ;r,-rLtr { t "t .5 .r-:,! .f ol-F F} rc 6Lrc ,i i4;l or'iar al n i a5 c;lc.c9, ,lcL:* ,s-til -brl o9l.o tr:l g rrr PRP &ri l+ .-rL-rr ca' o9f -,,1 ni.+ urethral sling.:,os;9c rtp *PRP Jl,;rgllrt, &r; .a,Jtt 4l ,l "t-L= .51o a:iL- *, SF 4+$j 9 et,j.i:r.i il a/l ut u:7Ja ccrf slrL9 ,,: ,r-;-l .Srlrcl .5rL:>l .+ r$lt (# csJHi ,-->9." 'rilq:*+d ,lrl* jl F Y .J"5 .s"r*r + +i U Ll. cea ,:J ( mid urethral sling )orlsh-l SLrc a' c'.-;. .;,!L- ;*.: crlsL-l .;L;r tt a--tL tJ *:.> .5r; cLttili&l Jli rsl.r- - .:5)L" ,l o.r,i, "";s .st--\ - ,.#r-l .5rlrrl .5r1.:il ,r1 :g!.rf C'hlfAbstractIntroduction : Urinary incontinence (UI) is a relatively common condition in middle-aged andolder women. negatively impacts health-related quality of life. one the most promising methodsof SUI treatment, based on regeneration of the damaged rhabdosphincter, is cell based therapy.Pure platelet rich plasma (PRP) is a new and less invasive technique and extremely rich ingrowth factors and cytokines, which regulate tissue reconstruction however, there is no evidenceto support or oppose its use in women who sufler from SUI. The aim of this study wasassessment the effect of paraurethral injection of PRP.Materials and Methods : This is a pilot study conducted randomized controlled trial on 20women with SUI .10 of these women were randomly assigned to receive paraurethral injectionof PRP.and 10 to receive standard treatment of SUI (mid passessed according to cough test,Intemational Consultation on Incontinence Questionnaire-Urinary incontinence (ICIQ), andIncontinence Quality of Life Questionnaire (IQOL) and urogenital distress inventory (QIIDD.Results : Of the 10 patients in the experimental group, 7 patients (70%) had a partialimprovement after PRP injection, and 3 (30%) had almost no response .of the 10 patients in thecontrol (mid urethral sling surgery) group, 8 patients had cure and 2 patients had noimprovement . Of the 3 patients heated with the repeated dose of PRP, 2 patients recoveredcompletely. There u.ere significant differences betn,een the results of the questionnaires beforeand after the treatment in both groups, indicating the effectiveness of treatment in both gloups.but response to treatment In the sling goup was more than the PRP group, this difference wasstatistically signifi cant.Conclusion : According to the findings of this study, single-dose paraurethral injection of PRPcan lead to a partial improvement in stress urinary incontinence sy,rnptoms in patients, althoughthis was less effective than standard treatment (mid urethral sling). according to the results of thisstudy ,treatment with repeated doses of PRP in the two patients who cured completely, could beexpected to achieve better and more consistently even in comparison u,ith standard treatment .Keyword : stress urinar.v- incontinence_ Pure platelet rich plasma_ Mid urethral slingC

بررسی اثر تزریق پارا اورترال پلاسمای غنی شده از پلاکت بر درمان بی اختیاری استرسی ادرار در زنان مراجعه کننده به کلینیک بعثت کرمان در سال ۱۳۹۶

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