Poster presented at the 45th ESCP Symposium on Clinical Pharmacy. 4-6 October 2016, Oslo, NorwayN/

Auad, Rodrigo

Bezerra, Simone S.

Gomes, João F.

Guerreiro, Mara P.

Pessoa, N.

Sobrinho, J. L. Soares

English

Repositório Comum

Simone S. Bezerra*1, Mara P. Guerreiro2, 3, João F. Gomes4, N. Pessoa1, Rodrigo Auad5, J. L. Soares Sobrinho11Universidade	Federal	de	Pernambuco,	Brasil	|	2Unidade	de	Investigação	&	Desenvolvimento	em	Enfermagem	(ui&de),	Escola	Superior	de	Enfermagem	de	Lisboa,	Portugal	|	3	Centro	de	Investigação	Interdisciplinar	(CiiEM),	Instituto	Superior	de	Ciências	da	Saúde	Egas	Moniz,	Portugal|	4Faculdade	de	Ciências,	Universidade	de	Lisboa,	Portugal	|	5 Escola	Técnica	Estadual	Professor	Agamemnon Magalhães,	Brasil	|		*Email:	simonesbezerra@gmail.com45th ESCP Symposium on Clinical Pharmacy | Oslo 2016Background and ObjectiveSetting and MethodsMain Outcome MeasuresCure and discontinuation of treatment in a tuberculosis control state programme in Brazil: insights from dispensing dataResults• Only site A had an acceptable discontinuation rate, in light of the World Health Organization recommendations.• Pharmacists could use dispensing data to signal TB patients at-risk of discontinuation, and subsequently tailor interventions addressing its causes• Site B had the greater number of patients which discontinued treatment. Patients co-infected with TB and HIV are firstly referred to this site, which may explain this finding.• Our findings suggest the need of more intensive interventions in patients co-infected with TB and HIV, such as pharmaceutical care programmes.ConclusionsRates for cure• The effectiveness of tuberculosis (TB) control programmes depends critically on patients completing appropriate treatment. • This study aimed to outline the cure and discontinuation rates of patients enrolled in the Pernambuco Tuberculosis Control Programme (PECT), based on dispensing data.• Study was conducted in three sites in Recife, state of Pernambuco, Brazil.• Data were collected between 07-11/2014, through reports from the stock management software for public pharmacies (HORUS) for PECT outpatients (n=948; 232, 348 and 368 in sites A, B and C, respectively)• “Cure”  was defined by the software as medicines collection for three, six or nine consecutive months without interruption, depending on the treatment scheme.• “Discontinuation” was defined as a non-sequential collection of medicines or treatment interruption for two consecutive months or more. • Patients were assigned an “undetermined” status if treatment was ongoing.• Qui-squared test, Fisher’s exact test and bootstrap analysis were performed with R statistical computing. • Ethical approval was granted.Cure and discontinuation rates for PECT outpatients.SITE	A SITE	B SITE	C35.9 % 23.6 % 31.0 %Rates for treatment discontinuationSITE	A SITE	B SITE	C3.4% 27.8 % 9.0 %• Discontinuation rates were significantly different among the sites A, B and C (p< 0.05). • Bootstrap analysis showed that the overall the proportion of patients with an "undetermined" status in each site did not significantly change these differences.8 general practice units + 1 polyclinic1 hospital for medium-complexity  patients 1 hospital for high-complexity patients SITE A SITE B SITE C

Cure and discontinuation of treatment in a tuberculosis control state programme in Brazil: insights from dispensing data

https://comum.rcaap.pt/bitstream/10400.26/19684/1/Poster08_MGuerreiro.pdf

Cure and discontinuation of treatment in a tuberculosis control state programme in Brazil: insights from dispensing data

Abstract

Similar works

Full text

Available Versions

Repositório Comum