Introduction: This systematic review examines Lipohypertrophy (LH) in patients presenting with Type 1/2 Diabetes (T1/2DM) in relation to education and injection techniques. LH is a condition, which occurs in diabetes individuals at injection sights. The most common method used is palpation in detecting LH, however preventing LH can be challenging due to a number of risk factors associated with LH.Method: Seven electronic databases were systematically searched for the most appropriate studies to be included. Articles were identified using Critical Appraisal Skills Programme (CASP) for eligibility. Key words were used to search the database. A PRISMA-based systematic review was used to identify studies. Results: A total of 49 studies were identified for consideration for this review, to consolidate the studies the abstracts were examined and from these 8 studies were deemed appropriate. Three themes identified from the studies were selected: Theme 1, Risk factors in the development of LH; Theme 2, Patient education influences the development of LH and Theme 3, Do injec¬tion techniques cause LH?Conclusion: There are number of risk factors associated with the cause of LH. Education plays a key role in the prevention of LH although this is not without its limitations. Further selective studies are required in order to establish if there is one stand¬alone factor
