An ethnobotanical survey carried out in the district of North Cachar hills, Assam, North East India during the period of February 2006 – November 2006, has revealed 34 species of plants to be threatened in several parts of the country, and in the district itself. More than 6 species of plants are included in the red Data Book of Indian Plants, 5 numbers of species have already been included in the Red Data List of the IUCN. 13 species documented in the present paper have not been reported about its threat status earlier, but are now threatened in the district. These plants are used in various ways such as, medicinal, wild edibles, ornamentals, building materials and other miscellaneous uses in their daily life. Because of the declining population of species like, Taxus baccata, Renanthera inschootiana, Swertia chirata etc., the area warrants conservation in order to preserve them from extinction. The present paper documents on the botanical name, parts used, local name, and also compares the threat status relative to other regions of the country as per IUCN Guidelines