A novel Radial Basis Function Network (RBFN) assisted Decision-Feedback aided Space-Time Equalizer (DF-STE) designed for receivers employing multiple antennas is proposed. The Bit Error Rate (BER) performance of the RBFN aided DF-STE is evaluated when communicating over correlated Rayleigh fading channels, whose Channel Impulse Response (CIR) is estimated using a Kalman filtering based channel estimator. The proposed receiver structure outperforms the linear Minimum Mean-Squared Error benchmarker and it is less sensitive to both error propagation and channel estimation errors