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Chemistry of Bridged Vitamin K Model Compounds

Abstract

Color poster with text, graphs, diagrams, and charts.Warfarin (Coumadin) has been in extensive clinical use since 1954. Although widely prescribed, warfarin is associated with a high incidence of adverse drug events (ADEs). This study continues research begun in 2009 when two vitamin K analogues (UWEC-K1 and UWEC-K2) that can potentially act as a warfarin agonist, were discovered.University of Wisconsin--Eau Claire Office of Research and Sponsored Programs; WiSys Technology Foundation

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