Efek Antiplasmodium Ekstrak Kulit Batang Asam Kandis (Garcinia Parvifolia Miq) Yang Diberikan Secara Intraperitoneal Pada Mencit Yang Diinfeksi Dengan Plasmodium Yoelii

Abstract

This study is trying to assess the effect of the stem bark extract of Garcinia parvifolia Miq on Plasmodium yoelii infected mice. Thirty mice, all male, were inoculated by Plasmodium yoelii.  They were randomly allocated into 6 groups of 5 mice and each  group was treated with G. parvifolia¢s extract of 100 mg/kgBW/day, 300 mg/kgBW/day, 500 mg/kgBW/day and 1000 mg/kgBW/day respectively.  Each groups was treated for the periode of 4 days after inoculation of P. yoelii.  The degree of parasitemia were examined daily using thin blood smears up to 4 days from the inoculation and were analyzed by log-probit method. The results showed that the ethanol extract displayed ED50 value less than 100 mg/kgBB/day