Spirituality is a very important issue in patients with chronic renal failure undergoing hemodialysis. The purpose of this qualitative study was to explore the spirituality experience of patients with chronic renal failure undergoing hemodialysis. The design of this study is phenomenology. Data were collected through in-depth interviews that conducted with 10 participants selected from renal unit of RSUP. H. Adam Malik and RSUD dr. Pirngadi Medan hospital based on criteria including age more than 18 years old, undergoing hemodialysis more than 3 months, composmentis and reguler hemodialysis 2 times a week. The collected data were analyzed using Colaizzi apporach to analysis. The results of this study showed four including being closer to God, the support of the people nearby, had great hopes for recovery, and willingly accept the illness. This study suggested the dialysis nurses to create program to support spiritual activity