Supernovae are incredibly energetic events which drive the dynamic state of the interstellar medium and accelerate cosmic rays up to energies of a few PeV. I present multi-wavelength observations constraining the shocks, chemistry, dust grain processing, and magnetic fields in a large sample of supernova remnants interacting with dense clouds. These are among the most luminous Galactic sources detected by the Fermi Gamma-Ray Space Telescope. Surprisingly, spectral breaks are seen between GeV and TeV energies. Radio spectral breaks have also been detected for a few remnants, providing clear evidence that supernovae are a significant source of hadronic cosmic rays in the Galaxy. Resolving the origin of these spectral breaks will allow the physics of cosmic ray acceleration and diffusion to be probed