We study the mobility and the diffusion coefficient of an inertial tracer advected by a two-dimensional incompressible laminar flow, in the presence ofthermal noise and under the actionof an external force. We show, with extensive numerical simulations, that the force-velocity rela-tion for the tracer, in the nonlinear regime, displays complex and rich behaviors, including negativedifferential and absolute mobility. These effects rely upon asubtle coupling between inertia andapplied force which induce the tracer to persist in particular regions of phase space with a velocityopposite to the force. The relevance of this coupling is revisited in the framework of non-equilibriumresponse theory, applying a generalized Einstein relationto our system. The possibility of experi-mental observation of these results is also discussed