Perbandingan Kualitas Spermatozoa Tikus Wistar (Rattus Norvegicus) Yang Diberi Paparan Asap Rokok Dengan Asap Rokok Elektronik

Abstract

: Cigarette smoke contains three main components, carbon monoxide, nicotine, and tar which can cause disturbances in spermatogenesis. Smoke electronic cigarette contains three main components, nicotine, propylene gycol, and glyceryn which can cause disturbances in spermatogenesis. The purpose of this experiment is to compare the quality of spermatozoa Wistar rats by exposure to cigarette smoke and electronic cigarette smoke. This study is an experimental study using an approach of post test only control group design. Subject of the study were 9 rats Wistar male (Rattus norvegicus) were divided into 3 groups: group P0 is not given exposure to cigarette smoke and smoke the electronic cigarette, the group P1 is given exposure to smoke cigarettes 2 rods per day, group P2 is given exposure to smoke an electronic cigarette for two rods lit cigarette. Treatment was done for 50 days. The results showed the concentration of spermatozoa is difference between the treatment groups, but statistical analysis groups P0 and P1 showed a non-significant (p = 0.229), P0 and P2 group (p = 0.559), P1 and P2 group (p = 0.879). Motility P0 with P2 group (p = 0.008) and group P1 and P2 group (p = 0.026) showed significant differences which means there is a treatment effect on motility. While groups of P0 with P1 group (p = 0.209) did not show significant differences which means there is no treatment effect on motility. Morphology Control with treatment group 1 (p = 0.098) while the control group with treatment 2 (p = 0.004) it shows the morphology of the group P0 to P1 has no effect while the P0 to P2 there is an influence on the treatment