Introduction: Various studies have shown the benefi cial effects of green tea, not only on cardiovascular diseases butalso on type 2 diabetes. Method: In this study, the preparation of green tea water extract has been standardized to (-)-epigalocatechin gallate (EGCG), the major component of green tea. The role of green tea water extract on blood fl uidityand diabetes diseases has been studied in 13 Fructose-Fed Rat (FFR). The rats were given high fructose diet ad libitumfor one week and then combination with green tea water extract every day for 6 days. Results: The results show, greentea water extract can reduces 100 μL blood passage times of wistar rat signifi cantly (p<0.01) by Micro-Channel ArrayFlow Analyzer (MC-FAN) instrument. Green tea water extract also had strong effect in reducing abdominal fat (p<0.05),blood glucose level (p<0.01) and body weight (p<0.01). Discussion: These results suggest that green tea water extractmay has benefi cial effects for the treatment of diabetes and reduce blood viscosity