System calibrates and records the responses of a nuclear magnetic resonance spectrometer. Calibration markers which have a highly stable frequency source are utilized to maintain frequency stability

Cohen, E. A.

Manatt, S. L.

English

NASA Technical Reports Server

Sharp 
Channel	 Beat 
No. 1	 Calibration 
Patterns
I Usual 1 Channel I NMR	 I No. 2 Spectrum  
April 1970
	 Brief 70-10086 
. NASA TECH BRIEF 
NASA Tech Briefs are issued to summarize specific innovations derived from the U.S. space program, - 
to encourage their commercial application. Copies are available to the public at 15 cents each 
from the Clearinghouse for Federal Scientific and Technical Information, Springfield, Virginia7 22151. 
Precise Audio-Frequency Markers for Nuclear

Magnetic Resonance Spectra 
Analogue
 H Audio  Amplifier	 PulseGenerator 	 Audio Sweep Device
Output	
I ToNMR 
Spectrometer	
Balanced	 Frequency 
System	
Mixer	 Synthesizer 
Channel No. 1 
Detected	 Channel No. 2	 Dual
 Output of	 Channel 
Chart NMR Spectrometer	
Recorder 
The problem: 
To design a system for simultaneously calibrating 
and recording the responses of a nuclear magnetic 
resonance spectrometer. 
The solution: 
Utilize calibration markers which have the stabil-
ity of a highly stable frequency source. Frequency 
stability must be maintained to one part in 10 in the
frequency range of 500 to 3500 Hz, and about one 
part in 106 in the frequency range of 3500 to 
10,000 Hz. 
How it's done: 
The method described in this Tech Brief depends 
on the beating of an unknown frequency (the fre-
quency being swept) against a known, very stable 
frequency.
(continued overleaf) 
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Aeronautics and Space Administration. Neither the United States 	 information contained in this document, or warrants that such use 
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https://ntrs.nasa.gov/search.jsp?R=19700000082 2020-03-17T00:23:30+00:00Z
The figure is a block diagram which shows how the 
system works. The audio amplifier amplifies the 
sweep frequency of the nuclear magnetic resonance 
(NMR) spectrometer. This output triggers the pulse 
generator at the sweep frequency. The pulses are fed 
to a balanced mixer which also receives pulses from 
the stable frequency source. The difference between 
the harmonic of the swept frequency and the fre- 
quency source can be displayed as a sharp beat 
pattern along with the NMR signal on the dual channel 
chart recorders. The operator, by manually stepping 
the frequency source, can easily exhibit per unit time, 
or chart division, or per unit frequency, as many sharp 
beat patterns as are necessary. 
Notes: 
I. This invention may be of interest to personnel 
working in laboratories which utilize nuclear 
magnetic resonance spectrometers, or which ,re- 
quire high-precision-frequency-sweep calibrations 
(at least one part in 106 for swept-frequencies 
up to 10 K Hz).
2. Requests for further documentation may be di-
rected to:
Technology Utilization Officer 
NASA Pasadena Office 
4800 Oak Grove Drive 
Pasadena, California 91103 
Reference: TSP70-10086 
Patent status: 
Inquiries about obtaining rights for the commercial 
use of this invention may be made to NASA, Code 
GP, Washington, D.C. 20546. 
Source: Edward A. Cohen and Stanley L. Manatt of

Caltech/Jet Propulsion Laboratory

under contract to

NASA Pasadena Office

(N PO- l 1147)
is 
. 
Li 
Brief 70-10086	 Category 02


Precise audio-frequency markers for nuclear magnetic resonance spectra

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