The invention relates to the field of poly- and oligosaccharides and their nutritional effects. In particular, it relates to the application of a-glucanotransferases in methods for preparing dietary fibers, including prebiotic oligosaccharides, and to novel oligosaccharides obtainable thereby. Provided is a method for producing a mixture of gluco-oligosaccharides having one or more consecutive (alpha 1 to 6) glucosidic linkages and one or more consecutive (alpha 1 to 4) glucosidic linkages, comprising contacting a poly- and/or oligosaccharide substrate comprising at least two (alpha 1 to 4) linked D-glucose units with an alpha-glucanotransferase capable of cleaving (alpha 1to 4) glucosidic linkages and making new (alpha 1 to 4) and (alpha 1 to 6) glucosidic linkages. Also provided are (isolated) gluco-oligosaccharides obtainable thereby, and their application in nutritional and cosmetic compositions

Dijkhuizen, Lubbert

Dobruchowska, Justyna Malgorzata

Kamerling, Johannis Paulus

Kralj, Slavko

Leemhuis, Reinder Johannes

van der Maarel, Marc Jos Elise Cornelis

The invention relates to the field of poly- and oligosaccharides and their nutritional effects. In particular, it relates to the application of a-glucanotransferases in methods for preparing dietary fibers, including prebiotic oligosaccharides, and to novel oligosaccharides obtainable thereby. Provided is a method for producing a mixture of gluco-oligosaccharides having one or more consecutive (alpha 1 to 6) glucosidic linkages and one or more consecutive (alpha 1 to 4) glucosidic linkages, comprising contacting a poly- and/or oligosaccharide substrate comprising at least two (alpha 1 to 4) linked D-glucose units with an alpha-glucanotransferase capable of cleaving (alpha 1to 4) glucosidic linkages and making new (alpha 1 to 4) and (alpha 1 to 6) glucosidic linkages. Also provided are (isolated) gluco-oligosaccharides obtainable thereby, and their application in nutritional and cosmetic compositions.</p

Proceedings - University of Groningen

   University of GroningenGlucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing themDijkhuizen, Lubbert; van der Maarel, Marc Jos Elise Cornelis; Kamerling, Johannis Paulus;Leemhuis, Reinder Johannes; Kralj, Slavko; Dobruchowska, Justyna MalgorzataIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2010Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkhuizen, L., van der Maarel, M. J. E. C., Kamerling, J. P., Leemhuis, R. J., Kralj, S., & Dobruchowska, J.M. (2010). Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidicbonds, use thereof, and methods for providing them. (Patent No. WO2010128859).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 29-10-2022

English

Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , and methods for providing them:Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidic bonds, use thereof, and methods for providing them

Dissertations of the University of Groningen

   University of GroningenGlucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing themDijkhuizen, Lubbert; van der Maarel, Marc Jos Elise Cornelis; Kamerling, Johannis Paulus;Leemhuis, Reinder Johannes; Kralj, Slavko; Dobruchowska, Justyna MalgorzataIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2010Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkhuizen, L., van der Maarel, M. J. E. C., Kamerling, J. P., Leemhuis, R. J., Kralj, S., & Dobruchowska, J.M. (2010). Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidicbonds, use thereof, and methods for providing them. (Patent No. WO2010128859).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 10-03-2023

ARTS repository - University of Groningen

   University of GroningenGlucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing themDijkhuizen, Lubbert; van der Maarel, Marc Jos Elise Cornelis; Kamerling, Johannis Paulus;Leemhuis, Reinder Johannes; Kralj, Slavko; Dobruchowska, Justyna MalgorzataIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2010Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkhuizen, L., van der Maarel, M. J. E. C., Kamerling, J. P., Leemhuis, R. J., Kralj, S., & Dobruchowska, J.M. (2010). Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidicbonds, use thereof, and methods for providing them. (Patent No. WO2010128859).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 31-10-2023

   University of GroningenGlucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing themDijkhuizen, Lubbert; van der Maarel, Marc Jos Elise Cornelis; Kamerling, Johannis Paulus;Leemhuis, Reinder Johannes; Kralj, Slavko; Dobruchowska, Justyna MalgorzataIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2010Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkhuizen, L., van der Maarel, M. J. E. C., Kamerling, J. P., Leemhuis, R. J., Kralj, S., & Dobruchowska, J.M. (2010). Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidicbonds, use thereof, and methods for providing them. (Patent No. WO2010128859).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 08-06-2022

University of Groningen

   University of GroningenGlucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , andmethods for providing themDijkhuizen, Lubbert; van der Maarel, Marc Jos Elise Cornelis; Kamerling, Johannis Paulus;Leemhuis, Reinder Johannes; Kralj, Slavko; Dobruchowska, Justyna MalgorzataIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2010Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkhuizen, L., van der Maarel, M. J. E. C., Kamerling, J. P., Leemhuis, R. J., Kralj, S., & Dobruchowska, J.M. (2010). IPC No. C12P 19/ 04 A I. Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidicbonds, use thereof , and methods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and(alpha 1to 6) glycosidic bonds, use thereof, and methods for providing them. (Patent No. WO2010128859).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 26-12-2020

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Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , and methods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidic bonds, use thereof, and methods for providing them

https://pure.rug.nl/ws/files/144703308/WO2010128859_A2.pdf

Glucose-oligosaccharides comprising (al?6) and (al?4) glycosidic bonds, use thereof , and methods for providing them: Gluco-oligosaccharides comprising (alpha 1 to 4) and (alpha 1to 6) glycosidic bonds, use thereof, and methods for providing them

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