We consider the fourth-order spectral problem y4
x−qxy
x λyx, x ∈ 0, l with spectral
parameter in the boundary condition. We associate this problem with a selfadjoint operator in
Hilbert or Pontryagin space. Using this operator-theoretic formulation and analytic methods,
we investigate locations in complex plane and multiplicities of the eigenvalues, the oscillation
properties of the eigenfunctions, the basis properties in Lp0, l, p ∈ 1, ∞, of the system of root
functions of this problem