Trabalho apresentado no Annual European Congress of Rheumatology (EULAR 2017), 14-17 junho de 2017, Madrid, EspanhaN/

Aguiar, R.

Branco, J.C.

Cruz, Eduardo Brazete

Kiltz, U.

Machado, P.M.

Pimentel-Santos, F.

Ramiro, S.

Rodrigues Manica, S.

Sepriano, A.

Sousa, S.

English

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THU0685 (2017)ASAS HEALTH INDEX FOR PATIENTS WITHSPONDYLOARTHRITIS: TRANSLATION INTO PORTUGUESE,VALIDATION, AND RELIABILITYS. Rodrigues Manica , E. Cruz , S. Ramiro , S. Sousa , R. Aguiar , A.Sepriano , P.M. Machado , U. Kiltz , J.C. Branco , F.M. Pimentel-SantosCEDOC - NOVA Medical School | Faculdade de Ciências Médicas, NOVA Universityof Lisbon Rheumatology Department, Hospital Egas Moniz, Centro Hospitalar de LisboaOcidental, Lisbon, Lisbon Escola Superior de Saúde de Setúbal, Instituto Politecnico de Setúbal, Setúbal,Portugal Rheumatology, Leiden University Medical Center, Leiden, Netherlands Hospital Garcia de Orta, Almada Centro Hospitalar Baixo Vouga, Hospital de Aveiro, Aveiro, Portugal Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases,University College London, London, United Kingdom Rheumazentrum Ruhrgebiet, Herne, GermanyBackground: The Assessment of SpondyloArthritis international Society Health Index (ASAS HI), is aunidimensional questionnaire, that includes 17 items, measuring functioning and health in patients withspondyloarthritis (SpA) (1). At the beginning of this project, only an English version of the instrumentexisted.Objectives: The aim of this study was to conduct the cross-cultural adaptation of the ASAS-HI intoEuropean Portuguese language and investigate its reliability and validity in a sample of Portuguesepatients with SpA.Methods: The ASAS-HI has a range from 0 (best health state) to 17 (worst health state). Thequestionnaire was first translated and then back translated following published guidelines. Patientsfulfilling ASAS classification criteria for either axial (axSpA) or peripheral SpA (pSpA) were included.Reliability was assessed through internal consistency coefficient, and internal consistency was assessedusing Cronbach's alpha. Construct validity was assessed through Spearman's correlation analysesbetween the ASAS-HI and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), BathAnkylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Disease Activity Score-CRP(ASDAS-CRP), and the Short Form (36) Health Survey (SF-36) (physical) SF-36 (physical) for convergentvalidity and between the ASAS-HI and the HAD-S Anxiety/Depression, and SF-36 (mental) for divergentvalidity. Discriminative validity was tested comparing the ASAS-HI across ASDAS-CRP disease activitystates using the Kruskal–Wallis test.Results: In total, 86 patients were included: 65% male, mean (SD) age 47.1 (12.9) years, symptomduration 11.4 (11.0) years, BASDAI 3.1 (2.1), BASFI 2.2 (2.6), ASDAS-CRP 2.2 (0.8). The diagnosis ofaxSpA was established in 58 patients (AS =45, nr-axSpA =13) and of pSpA in 28 patients. The forwardbackward translation was successful and qualitative interviews raised no further comments of theBookmarked1,2 3 4 5 61,4 7 8 1,2 1,212345678patients. The total mean score of the ASAS-HI was 4.6 (3.8). The ASAS- HI showed an excellent test-retest reliability (n=72) (ICC=0.93: 95% CI=0.89;0.96, p<0.001) and a good internal consistency(Cronbachs-α of 0.87). According to the predefined hypothesis, the ASAS-HI correlated strongly with theBASDAI (0.76, p<0.001), SF-36 (physical) (-0.75, p<0.001), moderately well with the HAD-S Anxiety (0.41,p<0.001), and SF-36 (mental) (-0.44, p<0.001) (Table 1), and showed a good discriminatory capacityacross the different levels of disease activity (p<0.001) (Table 2).Conclusions: The findings of this study showed that the Portuguese version of the ASAS –HI is acomprehensible questionnaire that is reliable and valid. Therefore, its use can be recommended, both forclinical practice and research purposes, to assess the state of health and functioning in Portuguese SpApatients. Future research is needed to evaluate the responsiveness of the ASAS-HI in SpA patients.References:Kiltz U et al. Ann Rheum Dis. 2015;74(5):830–5.Disclosure of Interest: None declaredDOI: 10.1136/annrheumdis-2017-eular.3927Citation: Annals of the Rheumatic Diseases, volume 76, supplement 2, year 2017, page 466Session: Validation of outcome measures and biomarkers , (Poster Presentations)

Asas health index for patients with spondyloarthritis: translation into portuguese, validation, and reliability

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Asas health index for patients with spondyloarthritis: translation into portuguese, validation, and reliability

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