Development of semi-permanent package and performance test system for electroceutical research

Abstract

Drug resistance that can be occurred by various causes makes it impossible for the patient to escape from the diseases. To solve this problem, Electroceutical, which modulates the neuronal activity with electrical stimulation, has received attention. However, it is necessary to use an implantable device to deliver a precise stimulus to the target. We, therefore, developed the hermetic packaging technique for long-term animal experiments and tested the waterproof performance of the prototype with building a human tissue mimicking phantom. Finally, we have confirmed the performance of the implantable package that can operate internal components normally for over a year.2