Cáceres, Carla E

Rapti, Zoi

Stewart, Tara

English

ISU ReD: Research and eData

Talk Title: Markov models reveal host controls of within-host disease dynamics The within-host processes that govern a parasite’s establishment, development, and reproduction are often unknown. Hosts have evolved a series of immunological traits to defend against parasites, but how important are immune defenses for regulating host-parasite interactions? By pairing longitudinal observational data with a continuous-time Markov-model, we evaluated the consequences of immune defenses for infection outcomes in a host-parasite system, the zooplankton host, Daphnia dentifera, and its fungal parasite, Metschnikowia bicuspidata. Implementation of our Resistance Clearance Markov model (RCM model) shows the importance of multiple immunological defenses for determining infection outcomes and illustrates the within-host dynamics of the Daphnia-Metschnikowia interaction.     	  

Markov models reveal host controls of within-host disease dynamics

https://ir.library.illinoisstate.edu/cgi/viewcontent.cgi?article=1172&amp;context=beer

Markov models reveal host controls of within-host disease dynamics

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ISU ReD: Research and eData