Bekkouche, N.S.

Godoy, S.M.

Gottlieb, S.S.

Harris, K.M.

Kop, W.J.

Krantz, D.S.

Wawrzyniak, A.J.

Whittaker, K.S.

NARCIS 

Depression, cardiovascular symptom reporting, and functional status in heart failure patients (abstract)

Tilburg University Repository

    Tilburg UniversityDepression, cardiovascular symptom reporting, and functional status in heart failurepatients (abstract)Wawrzyniak, A.J.; Harris, K.M.; Whittaker, K.S.; Bekkouche, N.S.; Godoy, S.M.; Kop, W.J.;Gottlieb, S.S.; Krantz, D.S.Published in:Cleveland Clinic Journal of MedicinePublication date:2011Document VersionPublisher's PDF, also known as Version of recordLink to publication in Tilburg University Research PortalCitation for published version (APA):Wawrzyniak, A. J., Harris, K. M., Whittaker, K. S., Bekkouche, N. S., Godoy, S. M., Kop, W. J., Gottlieb, S. S., &Krantz, D. S. (2011). Depression, cardiovascular symptom reporting, and functional status in heart failurepatients (abstract). Cleveland Clinic Journal of Medicine, 78(Suppl 1), S83a.General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright ownersand it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.            • Users may download and print one copy of any publication from the public portal for the purpose of private study or research.            • You may not further distribute the material or use it for any profit-making activity or commercial gain            • You may freely distribute the URL identifying the publication in the public portalTake down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Download date: 12. May. 2021CLEVELAND CLINIC JOURNAL OF MEDICINE         VOLUME 78 • SUPPLEMENT 1         AUGUST 2011    S83aAbstract 8Depression, Cardiovascular Symptom Reporting, and Functional Status in Heart Failure Patients Andrew J. Wawrzyniak,1 Kristie M. Harris,1 Kerry S. Whittaker,1 Nadine S. Bekkouche,1 Sarah M. Godoy,1 Willem J. Kop,2 Stephen S. Gottlieb,2 and David S. Krantz11Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, and 2Division of Cardiology, University of Maryland School of Medicine, Baltimore, MDBackground: Depression is common among heart failure (HF) patients and can infl uence reporting of cardiovascular symptoms; depression may precipitate psychosomatic symptom reporting and worsen functional health status. This study examines the relationship between depression and cardiovascular symptoms through self-reports and objective measures.Methods: Eighty-one patients (64 males; mean = 55.8 ± 11.2 years at baseline) with HF (ejection fraction ≤ 40) were examined at intake and again 3 months later. The Beck Depression Inven-tory (BDI) and the Kansas City Cardiomyopathy Questionnaire (KCCQ) as subjective measures along with the Six-Minute Walk Test (6MWT) as a measure of objective functional status were administered at both time points.Results: Baseline BDI scores correlated negatively with nine of the 10 subscales of the KCCQ (physical limitation: r = 0.44; symptom frequency: r = .52; symptom burden: r = 0.50; total symptoms: r = 0.53; self-effi cacy: r = 0.27, P = .019; quality of life: r = 0.72; social limitation: r = 0.56; clinical summary: r = 0.55; overall summary: r = 0.67; all P < .001 unless noted) but was not related to symptom stability. Mean BDI scores sig-nifi cantly decreased from baseline (13.6 ± 10.5) to 3 months (9.2 ± 7.7) indicating less depressive symptoms over 3 months (P > .001). In addition, changes in BDI scores and the KCCQ from baseline to 3 months were also negatively related to all KCCQ subscales (r range: 0.52 to 0.32, P < .05) except for symptom stability. Increasing BDI scores were related to decreased 6MWT performance (r = .33, P = .024); after controlling for age, gen-der, body mass index, current smoking status, diabetic status, and serum creatinine, only worsening BDI scores signifi cantly pre-dicted a decrease in distance walked on the 6MWT ( = .38, P = .017; overall model R2 = 0.18, P = .039 ) between baseline and 3-month follow-up.Conclusions: In HF patients studied prospectively, depres-sive symptoms were related to poorer self-reported HF symptoms at baseline; over time, increases in depression were related to increased subjective symptom reporting and worsening func-tional status. These fi ndings suggest that depression can nega-tively impact both subjective and objective health outcomes in HF patients; mechanisms of this association require further investigation.Young Investigator Research Award NomineeThe Young Investigator Research Award is a competition open to graduate students, postdoctoral fellows, residents, fellows, and junior faculty (within 2 years of their fi rst appointment). It is made possible by the continued support of Thomas F. Peterson, Jr., who also supports the Thomas F. Peterson, Jr. Center for Heart-Brain Research within the Earl and Doris Bakken Heart-Brain Institute at Cleveland Clinic. The 2010 recipient is Kyoung Suk Lee, PhD.

English

    Tilburg UniversityDepression, cardiovascular symptom reporting, and functional status in heart failurepatients (abstract)Wawrzyniak, A.J.; Harris, K.M.; Whittaker, K.S.; Bekkouche, N.S.; Godoy, S.M.; Kop, W.J.;Gottlieb, S.S.; Krantz, D.S.Published in:Cleveland Clinic Journal of MedicinePublication date:2011Document VersionPublisher's PDF, also known as Version of recordLink to publication in Tilburg University Research PortalCitation for published version (APA):Wawrzyniak, A. J., Harris, K. M., Whittaker, K. S., Bekkouche, N. S., Godoy, S. M., Kop, W. J., Gottlieb, S. S., &Krantz, D. S. (2011). Depression, cardiovascular symptom reporting, and functional status in heart failurepatients (abstract). Cleveland Clinic Journal of Medicine, 78(Suppl 1), S83a.General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright ownersand it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.            • Users may download and print one copy of any publication from the public portal for the purpose of private study or research.            • You may not further distribute the material or use it for any profit-making activity or commercial gain            • You may freely distribute the URL identifying the publication in the public portalTake down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Download date: 26. Sep. 2023CLEVELAND CLINIC JOURNAL OF MEDICINE         VOLUME 78 • SUPPLEMENT 1         AUGUST 2011    S83aAbstract 8Depression, Cardiovascular Symptom Reporting, and Functional Status in Heart Failure Patients Andrew J. Wawrzyniak,1 Kristie M. Harris,1 Kerry S. Whittaker,1 Nadine S. Bekkouche,1 Sarah M. Godoy,1 Willem J. Kop,2 Stephen S. Gottlieb,2 and David S. Krantz11Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, and 2Division of Cardiology, University of Maryland School of Medicine, Baltimore, MDBackground: Depression is common among heart failure (HF) patients and can infl uence reporting of cardiovascular symptoms; depression may precipitate psychosomatic symptom reporting and worsen functional health status. This study examines the relationship between depression and cardiovascular symptoms through self-reports and objective measures.Methods: Eighty-one patients (64 males; mean = 55.8 ± 11.2 years at baseline) with HF (ejection fraction ≤ 40) were examined at intake and again 3 months later. The Beck Depression Inven-tory (BDI) and the Kansas City Cardiomyopathy Questionnaire (KCCQ) as subjective measures along with the Six-Minute Walk Test (6MWT) as a measure of objective functional status were administered at both time points.Results: Baseline BDI scores correlated negatively with nine of the 10 subscales of the KCCQ (physical limitation: r = 0.44; symptom frequency: r = .52; symptom burden: r = 0.50; total symptoms: r = 0.53; self-effi cacy: r = 0.27, P = .019; quality of life: r = 0.72; social limitation: r = 0.56; clinical summary: r = 0.55; overall summary: r = 0.67; all P < .001 unless noted) but was not related to symptom stability. Mean BDI scores sig-nifi cantly decreased from baseline (13.6 ± 10.5) to 3 months (9.2 ± 7.7) indicating less depressive symptoms over 3 months (P > .001). In addition, changes in BDI scores and the KCCQ from baseline to 3 months were also negatively related to all KCCQ subscales (r range: 0.52 to 0.32, P < .05) except for symptom stability. Increasing BDI scores were related to decreased 6MWT performance (r = .33, P = .024); after controlling for age, gen-der, body mass index, current smoking status, diabetic status, and serum creatinine, only worsening BDI scores signifi cantly pre-dicted a decrease in distance walked on the 6MWT ( = .38, P = .017; overall model R2 = 0.18, P = .039 ) between baseline and 3-month follow-up.Conclusions: In HF patients studied prospectively, depres-sive symptoms were related to poorer self-reported HF symptoms at baseline; over time, increases in depression were related to increased subjective symptom reporting and worsening func-tional status. These fi ndings suggest that depression can nega-tively impact both subjective and objective health outcomes in HF patients; mechanisms of this association require further investigation.Young Investigator Research Award NomineeThe Young Investigator Research Award is a competition open to graduate students, postdoctoral fellows, residents, fellows, and junior faculty (within 2 years of their fi rst appointment). It is made possible by the continued support of Thomas F. Peterson, Jr., who also supports the Thomas F. Peterson, Jr. Center for Heart-Brain Research within the Earl and Doris Bakken Heart-Brain Institute at Cleveland Clinic. The 2010 recipient is Kyoung Suk Lee, PhD.

https://pure.uvt.nl/ws/files/1359456/MedPsy_Kop_Depression_abstract_CCJoM_2011.pdf

Depression, cardiovascular symptom reporting, and functional status in heart failure patients (abstract)

Abstract

Similar works

Full text

Available Versions

NARCIS

Tilburg University Repository

Tilburg University Repository