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Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening
Authors
L. Behrendt
M. Mazurenka
+3 more
Merve Meinhardt-Wollweber
Uwe Morgner
B. Roth
Publication date
1 January 2017
Publisher
American Institute of Physics Inc.
Doi
Cite
Abstract
A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening. © 2017 Author(s)
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Institutionelles Repositorium der Leibniz Universität Hannover
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Last time updated on 11/06/2018