It is to study the preparation process of inulin compound effervescent tablets by single factor experiments and optimize the type and amount of lubricants. The formula of the pH, effervescent time, sensory quality and stiffness were selected as the evaluation index. Meanwhile, the orthogonal tests were used to optimize the ratio of citric acid to sodium bicarbonate, the amount of sweetener and the amount of orange powder. The best preparation technology conditions of effervescent tablets were as follows: the ratio of citric acid to sodium bicarbonate 1.25︰1, inulin 27.8%, stevia 1%, orange powder 20%, PEG-
6000 1.6% and sodium chloride 3.4%. Under the optimal conditions, there was no sticking phenomenon during tablets preparation. Furthermore, all the quality indexes of the prepared effervescent tablets complied with the requirements of the “Chinese Pharmacopoeia”
