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Effects of DKPs on Gene Expression of the Antibacterial Substances in Bacillus amyloliquefaciens Q-426
Authors
权春善
杨学敏
+3 more
熊文
王建华
范圣第
Publication date
1 January 2012
Publisher
Abstract
目的:解淀粉芽孢杆菌Q-426在其生长过程中能够产生芬枯草菌素、依枯草菌素、枯草杆菌素等多种脂肽类抗菌物质。利用实时荧光定量PCR的方法考察细菌群体感应信号分子二酮哌嗪类化合物(diketopiperazines,DKPs)对脂肽类抗菌物质合成的调控作用。方法:当Q-426菌进入对数生长期中期,向发酵液中加入终浓度为5 mg/L的DKPs,并继续培养至48 h,并利用实时荧光定量PCR的方法进行抗菌物质mRNA表达水平的定量分析。结果:二酮哌嗪类化合物能够抑制抗菌活性物质相关基因的表达。  
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Institutional Repository of Yantai Institute of Coastal Zone Research, CAS
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oai:ir.yic.ac.cn:133337/5425
Last time updated on 18/09/2018
Institutional Repository of Yantai Institute of Coastal Zone Research, CAS
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oai:ir.yic.ac.cn:133337/26677
Last time updated on 24/06/2021
Institutional Repository of Yantai Institute of Coastal Zone Research, CAS
See this paper in CORE
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oai:ir.yic.ac.cn:133337/5724
Last time updated on 18/09/2018