CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
research
Recommendations for reporting ion mobility Mass Spectrometry measurements
Authors
Carlos Afonso
Perdita Barran
+8 more
Justin L. P. Benesch
Aivett Bilbao
Christian Bleiholder
Michael T. Bowers
Matthew F. Bush [u.v.m.]
Valérie Gabelica
Kevin Pagel
Alexandre A. Shvartsburg
Publication date
1 January 2019
Publisher
Doi
Cite
Abstract
Here we present a guide to ion mobility mass spectrometry experiments, which covers both linear and nonlinear methods: what is measured, how the measurements are done, and how to report the results, including the uncertainties of mobility and collision cross section values. The guide aims to clarify some possibly confusing concepts, and the reporting recommendations should help researchers, authors and reviewers to contribute comprehensive reports, so that the ion mobility data can be reused more confidently. Starting from the concept of the definition of the measurand, we emphasize that (i) mobility values (K0) depend intrinsically on ion structure, the nature of the bath gas, temperature, and E/N; (ii) ion mobility does not measure molecular surfaces directly, but collision cross section (CCS) values are derived from mobility values using a physical model; (iii) methods relying on calibration are empirical (and thus may provide method‐dependent results) only if the gas nature, temperature or E/N cannot match those of the primary method. Our analysis highlights the urgency of a community effort toward establishing primary standards and reference materials for ion mobility, and provides recommendations to do so. © 2019 The Authors. Mass Spectrometry Reviews Published by Wiley Periodicals, Inc
Similar works
Full text
Open in the Core reader
Download PDF
Available Versions
Institutional Repository of the Freie Universität Berlin
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:refubium.fu-berlin.de:fub1...
Last time updated on 23/07/2019