The set definition of distal cholangiocarcinomas and adenocarcinomas of the
pancreatic head is challenged by their close anatomical relation, similar
growth pattern, and corresponding therapeutic outcome. They show a mutual
development during embryologic organ formation and share phenotypic
characteristics. This review will highlight the similarities with regard to
the common origin of their primary organs, histopathological similarities, and
modern clinical management. Thus, we propose to subsume those entities under a
common superfamily
