A consensus statement by the Society for Cardiovascular Magnetic Resonance
(SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI)
Parametric mapping techniques provide a non-invasive tool for quantifying
tissue alterations in myocardial disease in those eligible for cardiovascular
magnetic resonance (CMR). Parametric mapping with CMR now permits the routine
spatial visualization and quantification of changes in myocardial composition
based on changes in T1, T2, and T2*(star) relaxation times and extracellular
volume (ECV). These changes include specific disease pathways related to
mainly intracellular disturbances of the cardiomyocyte (e.g., iron overload,
or glycosphingolipid accumulation in Anderson-Fabry disease); extracellular
disturbances in the myocardial interstitium (e.g., myocardial fibrosis or
cardiac amyloidosis from accumulation of collagen or amyloid proteins,
respectively); or both (myocardial edema with increased intracellular and/or
extracellular water). Parametric mapping promises improvements in patient care
through advances in quantitative diagnostics, inter- and intra-patient
comparability, and relatedly improvements in treatment. There is a multitude
of technical approaches and potential applications. This document provides a
summary of the existing evidence for the clinical value of parametric mapping
in the heart as of mid 2017, and gives recommendations for practical use in
different clinical scenarios for scientists, clinicians, and CMR
manufacturers