Using the "stimulus-delay-target" experimental model, the brain mechanism of visual-spatial attention shift after number processing was conducted on 13 participants by using event-related potentials (ERP) technology. Results show that influence of the number processing on the spatial attention is indexed by the P3 component; parietal lobes at both sides may be the main neural substrate for number processing and spatial attention, and the numerical-spatial interaction mainly occurs in the response selection stage.;Using the "stimulus-delay-target" experimental model, the brain mechanism of visual-spatial attention shift after number processing was conducted on 13 participants by using event-related potentials (ERP) technology. Results show that influence of the number processing on the spatial attention is indexed by the P3 component; parietal lobes at both sides may be the main neural substrate for number processing and spatial attention, and the numerical-spatial interaction mainly occurs in the response selection stage.</p