The main aim of the Study was to identify 'Availability and Use of Information Resources in Medical Libraries by Pre-Clinical students in Selected Universities in Edo State'384 respondents participated in the study. Questionnaire were used as instruments for data collection.Results were analyzed using simple percentages. Textbooks, dictionaries and journals are some of the available information resources in medical libraries studied.Low computer literacy to browse the internet was the major problem associated with the use of the information resources. The study conclude that creating an awareness of information resources is essential for maximum utilization of the information resources in the medical librarie