Automatic Control and Systems Engineering, University of Sheffield
Abstract
It remains unclear how visual information is co-processed
by different layers of neurons in the retina. In particular, relatively little is known how retina translates vast environmental light changes into
neural responses of limited range. We began examining this question in a bottom-up way in a relatively simple °y eye. To gain understanding of how complex bio-molecular interactions govern the conversion of light input into voltage output (phototransduction), we are building a
biophysical model of the Drosophila R1-R6 photoreceptor. Our model, which relates molecular dynamics of the underlying biochemical reactions to external light input, attempts to capture the molecular dynamics of
phototransduction gain control in a quantitative way
